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This week’s episode is sponsored by the University of California, committed to creating solutions to today’s environmental challenges. To uncover groundbreaking research from the University of California, visit www.slate.com/breakthroughs. This episode is also sponsored by PBS, presenting Wolf Hall, based on the best-selling book series about political intrigue in the Tudor court. Wolf Hall airs on Masterpiece on PBS, Sunday, April 5, at 10/9 central.

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For this week’s Slate Plus bonus segment, the hosts discuss Trevor Noah’s controversial tweets. Slate Plus members get an ad-free version of this podcast with bonus segments. Visit slate.com/gabfestplus and try it free for two weeks.

On this week’s Slate Political Gabfest, Emily Bazelon, John Dickerson, and David Plotz discuss the Obama administration’s historic agreement on the framework of a nuclear deal with Iran, the fallout from Indiana’s and Arkansas’ controversial Religious Freedom Restoration acts, and the retirement of Senate Minority Leader Harry Reid, D-Nevada.

Here are some of the links and references mentioned during this week’s show:

• The U.S. and Iran agree to a detailed framework for a nuclear agreement. President Obama calls the framework “historic” and a “good deal” while Congress reacts with renewed skepticism.
• Dennis Ross examines several noteworthy points of the framework. Slate’s Fred Kaplan argues that anyone who denounces the framework is not a serious person or is pursuing a parochial agenda.
• Meet the two negotiators who used physics to help craft the historic framework.
• What’s going on with all of these Religious Freedom Restoration acts and why are they such a big deal? Given what happened to Memories Pizza, is it ever OK to refuse service based on one’s religious beliefs?
• Slate’s  Ben Mathis-Lilley explores the latest developments in Indiana and Arkansas.
• Jeb Bush (along with several other Republican White House hopefuls), while quick to initially defend RFRAs, has since tempered his support. Ronald Brownstein discusses how social issues will inform the 2016 presidential election.
• Sen. Harry Reid, D-Nevada, announced his retirement, opening the door for Sen. Chuck Schumer, D–New York, to replace him as minority leader. Will Reid’s legacy be more about filibuster reform or dirty politics?
• Who is Chuck Schumer and why does Wall Street love him?
• Should Elizabeth Warren, D-Massachusetts, be the new Senate minority leader instead?

Emily chatters about Ali Smith’s award winning novel How to Be Both.

John chatters about the epic nonstop flight, from New England to South America, of the blackpoll warbler.

David chatters about his rage—caused by the regular delays he experiences during his weekly travels throughout New York City.

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The email address for the Political Gabfest is gabfest@slate.com. (Email may be quoted by name unless the writer stipulates otherwise.)

Podcast production by Mike Vuolo. Links compiled by Tarik Barrett.