Misoprostol (trade name Cytotec) is licensed in the United States and almost everywhere else as a drug that protects the lining of the stomach from the effects of nonsteroidal anti-inflammatories—aspirin, Motrin, Naprosyn, Aleve, Indocin, and many others. Misoprostol is the only drug currently available with this stomach-protecting effect. In the United States, it is legal and common for a drug that is licensed for one purpose to be used "off-label" for another purpose. The great majority of drugs used for children are prescribed off-label, since most medications are licensed only for adult use and no one cares to bear the cost of pediatric testing.