There are a ton of really good skeptical podcasts out there, like Skeptics' Guide to the Universe, Skepticality, Point of Inquiry, Skeptoid, George Hrab, and so on. These are generally professionally-done 'casts made by people with long experience in the field.
But they had to start somewhere, right? At some point in the past, these folks were just people who had something to say and wanted their voices heard. So if you're like that too -- opinionated, willing to back up your claims, and dying to get the message out -- but lack a platform, what can you do? Starting your own podcast can be daunting.
If that sounds fmailiar, then you should check out Skeptographers. This is a community-driven podcast where anyone can upload content and have it aired. Of course, there are some caveats; they can't simply take anything submitted, but there are guidelines on how to do it.
I think this is an interesting idea. The whole point of the internet is that it's egalitarian; people who have quality content can flourish, and if you suck, people won't listen. Well, usually. But that's the idea, anyway. A podcast like this can get people who otherwise don't have much of a voice online a chance to be heard. And if they're good, then they may break out and be followed. It's not without precedent; 365 Days of Astronomy has a similar basis.
So head over to Skeptographers, give it a listen (the pilot episode is already online) and if you have something to say, then say it.